Hiroto Miwa Selected Research

Peptic Esophagitis (Reflux Esophagitis)

7/2018	Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases.
1/2016	Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn.
4/2015	Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis.
8/2013	[Efficacy and safety of esomeprazole, compared with omeprazole, in maintenance therapy for reflux esophagitis -a phase III, multicenter, randomized, double-blind trial-].
3/2013	Histology of symptomatic gastroesophageal reflux disease: is it predictive of response to proton pump inhibitors?
2/2013	[Efficacy of esomeprazole compared with omeprazole in reflux esophagitis patients -a phase III, multicenter, randomized, double-blind, parallel-group trial-].
5/2012	Symptoms and quality of life in underweight gastroesophageal reflux disease patients and therapeutic responses to proton pump inhibitors.
3/2012	Combination of angiotensin II receptor blockers promotes proton pump inhibitor-based healing of reflux esophagitis.
3/2011	Effect of rabeprazole treatment on health-related quality of life and symptoms in patients with reflux esophagitis: a prospective multicenter observational study in Japan.
11/2010	Non-erosive reflux disease rather than cervical inlet patch involves globus.

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Hiroto Miwa Research Topics

Disease

28	Stomach Neoplasms (Stomach Cancer) 07/2021 - 01/2003
27	Gastroesophageal Reflux (GERD) 03/2022 - 08/2004
26	Neoplasms (Cancer) 04/2022 - 01/2003
20	Dyspepsia (Indigestion) 10/2022 - 11/2005
17	Peptic Esophagitis (Reflux Esophagitis) 07/2018 - 08/2004
15	Ulcerative Colitis 07/2021 - 11/2005
14	Inflammation (Inflammations) 11/2021 - 07/2002
14	Infections 10/2019 - 02/2002
13	Heartburn (Pyrosis) 01/2019 - 09/2009
10	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/2021 - 01/2012
10	Ulcer 01/2020 - 01/2009
9	Hypersensitivity (Allergy) 04/2022 - 08/2004
9	Pain (Aches) 04/2022 - 12/2006
9	Constipation 01/2021 - 12/2018
9	Non-Erosive Reflux Disease 08/2016 - 05/2007
8	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 04/2021 - 01/2012
8	Crohn Disease (Crohn's Disease) 01/2020 - 01/2004
7	Microsatellite Instability 12/2021 - 05/2012
7	Hemorrhage 03/2021 - 06/2011
7	Esophagitis 01/2021 - 08/2005
6	Diarrhea 01/2021 - 06/2012
5	Abdominal Pain (Pain, Abdominal) 04/2022 - 11/2009
5	Fibrosis (Cirrhosis) 11/2021 - 01/2008
5	Gastritis 01/2021 - 12/2006
5	Metaplasia 01/2020 - 05/2012
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 05/2005
5	Adenocarcinoma 01/2019 - 12/2010
5	Colitis 01/2019 - 01/2008
5	Neoplasm Metastasis (Metastasis) 01/2018 - 04/2009
5	Peptic Ulcer (Peptic Ulcers) 01/2017 - 12/2009
4	Carcinogenesis 07/2021 - 06/2007
4	Polyps 04/2021 - 01/2003
4	Pathologic Constriction (Stenosis) 12/2016 - 04/2009
3	Obesity 11/2021 - 09/2018
3	Adenoma (Adenomas) 04/2021 - 09/2012
3	Atrophic Gastritis 01/2020 - 01/2003
3	Visceral Pain 01/2013 - 04/2008
2	Non-alcoholic Fatty Liver Disease 11/2021 - 10/2021
2	Ascites 07/2021 - 01/2021
2	Alcoholic Fatty Liver 07/2021 - 01/2021
2	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021 - 01/2021
2	Dysbiosis 08/2020 - 01/2019
2	Clostridium Infections 04/2020 - 01/2018
2	Duodenal Ulcer (Curling's Ulcer) 07/2018 - 02/2004
2	Foreign Bodies (Foreign Body) 01/2018 - 05/2013
2	Diverticular Diseases 09/2017 - 10/2011

Drug/Important Bio-Agent (IBA)

29	Proton Pump InhibitorsIBA 03/2022 - 11/2004
23	AcidsIBA 04/2022 - 08/2004
14	Proteins (Proteins, Gene)FDA Link 07/2021 - 07/2004
11	Pharmaceutical PreparationsIBA 11/2021 - 08/2011
10	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2020 - 06/2011
9	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2017 - 02/2004
7	CytokinesIBA 05/2020 - 10/2008
5	Esomeprazole (Nexium)FDA Link 03/2022 - 02/2013
5	Tight Junction ProteinsIBA 10/2019 - 08/2004
5	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 07/2008
4	Dinoprostone (PGE2)FDA Link 01/2022 - 07/2015
4	1- (5- (2- fluorophenyl)- 1- (pyridin- 3- ylsulfonyl)- 1H- pyrrol- 3- yl)- N- methylmethanamineIBA 01/2021 - 08/2018
4	Infliximab (Remicade)FDA Link 01/2020 - 01/2010
4	S-1 plus cisplatinIBA 01/2019 - 08/2016
4	Lansoprazole (Prevacid)FDA LinkGeneric 01/2019 - 01/2008
4	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 07/2008
4	liu-jun-zi-tangIBA 08/2016 - 05/2010
4	Interleukin-33IBA 01/2016 - 04/2015
4	Rabeprazole (Aciphex)FDA Link 03/2015 - 03/2011
4	Omeprazole (Prilosec)FDA LinkGeneric 08/2013 - 01/2009
3	NivolumabIBA 07/2021 - 01/2021
3	Bile Acids and Salts (Bile Acids)IBA 04/2021 - 07/2012
3	minesaprideIBA 01/2021 - 01/2020
3	Anti-Bacterial Agents (Antibiotics)IBA 08/2020 - 11/2005
3	linaclotideIBA 01/2019 - 12/2018
3	Biomarkers (Surrogate Marker)IBA 09/2018 - 05/2012
3	Amoxicillin (Wymox)FDA LinkGeneric 08/2018 - 11/2004
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 07/2014
3	Monoclonal AntibodiesIBA 05/2016 - 05/2012
3	rebamipideIBA 08/2014 - 12/2006
3	Mitogen-Activated Protein KinasesIBA 01/2013 - 04/2008
3	ClaudinsIBA 01/2013 - 12/2008
3	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2012 - 03/2009
2	Messenger RNA (mRNA)IBA 12/2021 - 01/2016
2	Phenobarbital (Luminal)FDA Link 11/2021 - 12/2016
2	Antiviral Agents (Antivirals)IBA 07/2021 - 01/2021
2	CateninsIBA 04/2021 - 01/2015
2	Z 338IBA 02/2021 - 05/2017
2	Magnesium Oxide (Magnesia)FDA Link 01/2021 - 10/2019
2	Claudin-4IBA 08/2020 - 06/2012
2	Warfarin (Coumadin)FDA LinkGeneric 01/2020 - 09/2017
2	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 11/2016
2	C-Reactive ProteinIBA 01/2020 - 09/2012
2	Vancomycin FDA LinkGeneric 04/2019 - 01/2019
2	MucinsIBA 01/2019 - 10/2011
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2019 - 01/2017
2	AdiponectinIBA 09/2018 - 01/2016
2	Clarithromycin (Biaxin)FDA LinkGeneric 08/2018 - 11/2004
2	ProstaglandinsIBA 10/2017 - 03/2013
2	Interleukin-8 (Interleukin 8)IBA 07/2017 - 01/2016

Therapy/Procedure

44	Therapeutics 04/2022 - 02/2002
9	Drug Therapy (Chemotherapy) 11/2021 - 04/2009
6	Blood Component Removal (Apheresis) 02/2013 - 10/2007
4	Gastrectomy 04/2022 - 10/2010